Small Molecule Drug Discovery

Screen up to 100,000 compounds per day and rapidly identify active compounds

Assay Onboarding and Development

Our state-of-the-art fully automated robotic platform is set-up to accelerate your drug discovery process. Our system can efficiently run biochemical, phenotypic and cellular HTS assays in 384- or 1536-well formats.

Bring your own library or use one of our compund libraries in a platform that combines a comprehensive range of HTS screening technologies including fluorescence intensity, FRET, luminescence, BRET, absorbance, fluorescence polarization, TR-FRET, time-resolved fluorescence, Alpha screen, AlphaLISA, qPCR, mass spectrometry assays and more

Representative Hit Identification Workflow
Representative Hit Identification Workflow
Customer Onboarding - Intake and Assay Validation
Customer Onboarding - Intake and Assay Validation
Customer Onboarding - Intake and Assay Validation
RETESTING AND CONFIRMATIONRetesting and orthogonal assays
Customer Onboarding - Intake and Assay Validation

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Automation Module TST 1

Automation Module TST1

TST1 is used for biological testing. Biochemical as well as biophysical assays are carried out in this module. That is, TST1 tests the compounds synthesized in our smart labs for their intended activity in simplified assays that hopefully represent the disease. These would primarily be biochemical (without cells) due to lack of a temperature controlled incubator. The information from TST1 can be used to inform the design of compounds to better impact their target while minimizing side-effects through structure activity relationship (SAR) studies. TST1 is built for SAR and medium throughput screening (MTS).

Automation Module TST5

Automation Module TST5

TST5 is used for biological testing. Cell based and biochemical assays are carried out in this module. These could be biochemical (without cells) or cell-based (with cells). This workcell primary function is to rapidly find new starting materials for new lead discovery efforts via HTS. This workcell is capable of running both HTS and MTS campaigns up to 1 million compounds. Utilizing GNFWDII it is capable of adding and removing media on 1536 well plates, thereby extending the possible use for high content imaging assays.