Small Molecule Drug Discovery
Screen up to 100,000 compounds per day and rapidly identify active compounds
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SMALL MOLECULE DRUG DISCOVERY SERVICES
Hit discovery or hit identification in drug development is driven by the need to identify small molecules with desirable activity in a compound screen against a target. Our state-of-the-art fully automated robotic platform is set-up to accelerate your drug discovery process starting with robust, targeted hit identification services. Our system can efficiently run biochemical, phenotypic and cellular HTS assays in 384- or 1536-well formats.
Bring your own library or use one of our compound libraries in a small molecule hit identification and validation platform that combines a comprehensive range of HTS screening technologies including fluorescence intensity, FRET, luminescence, BRET, absorbance, fluorescence polarization, TR-FRET, time-resolved fluorescence, Alpha screen, AlphaLISA, qPCR, mass spectrometry assays and more.
Representative Hit Identification Workflow
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CUSTOMER ONBOARDINGCustom Assay Development of Assay Tansfer, or Off the Shelf Assay
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INTAKE AND ASSAY VALIDATIONAssay Feasibility, Miniaturization and Optimization
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HTS CAMPAIGNSingle Point Screen
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RETESTING AND CONFIRMATIONRetesting and orthogonal assays
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CHARACTERIZATIONSelectivity, and secondary assays
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